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Hypothesized Models of the CD28 and CD8a Hinge Regions (A) The... |  Download Scientific Diagram
Hypothesized Models of the CD28 and CD8a Hinge Regions (A) The... | Download Scientific Diagram

Cells | Free Full-Text | Hinge and Transmembrane Domains of Chimeric  Antigen Receptor Regulate Receptor Expression and Signaling Threshold
Cells | Free Full-Text | Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate Receptor Expression and Signaling Threshold

Engineering and Design of Chimeric Antigen Receptors - ScienceDirect
Engineering and Design of Chimeric Antigen Receptors - ScienceDirect

Cancers | Free Full-Text | Engineering Solutions for Mitigation of Chimeric  Antigen Receptor T-Cell Dysfunction
Cancers | Free Full-Text | Engineering Solutions for Mitigation of Chimeric Antigen Receptor T-Cell Dysfunction

Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate  Receptor Expression and Signaling Threshold
Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate Receptor Expression and Signaling Threshold

EP3115373A1 - Chimeric antigen receptors with an optimized hinge region -  Google Patents
EP3115373A1 - Chimeric antigen receptors with an optimized hinge region - Google Patents

Frontiers | How the Discovery of the CD4/CD8-p56lck Complexes Changed  Immunology and Immunotherapy
Frontiers | How the Discovery of the CD4/CD8-p56lck Complexes Changed Immunology and Immunotherapy

The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T  cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer |  Nature Communications
The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer | Nature Communications

Activity of sCAR hinge designs. (A) Cytotoxicity of sCAR-T cells with... |  Download Scientific Diagram
Activity of sCAR hinge designs. (A) Cytotoxicity of sCAR-T cells with... | Download Scientific Diagram

Fine Molecular Tuning of Chimeric Antigen Receptors through Hinge Length  Optimization | bioRxiv
Fine Molecular Tuning of Chimeric Antigen Receptors through Hinge Length Optimization | bioRxiv

CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8+ T-cell  Responses - ScienceDirect
CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8+ T-cell Responses - ScienceDirect

EP3115373A1 - Chimeric antigen receptors with an optimized hinge region -  Google Patents
EP3115373A1 - Chimeric antigen receptors with an optimized hinge region - Google Patents

Figure1. Structure of different chimeric antigen receptor (CAR)... |  Download Scientific Diagram
Figure1. Structure of different chimeric antigen receptor (CAR)... | Download Scientific Diagram

Incorporation of a hinge domain improves the expansion of chimeric antigen  receptor T cells | Journal of Hematology & Oncology | Full Text
Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells | Journal of Hematology & Oncology | Full Text

Antigenic Sensitivity of Membrane-Proximal Targeting Chimeric Antigen  Receptors can be Fine-Tuned through Hinge Truncation | bioRxiv
Antigenic Sensitivity of Membrane-Proximal Targeting Chimeric Antigen Receptors can be Fine-Tuned through Hinge Truncation | bioRxiv

The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T  cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer |  Nature Communications
The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer | Nature Communications

Frontiers | Lymphocytes in Cellular Therapy: Functional Regulation of CAR T  Cells
Frontiers | Lymphocytes in Cellular Therapy: Functional Regulation of CAR T Cells

Fine Molecular Tuning of Chimeric Antigen Receptors through Hinge Length  Optimization | bioRxiv
Fine Molecular Tuning of Chimeric Antigen Receptors through Hinge Length Optimization | bioRxiv

Cells | Free Full-Text | Hinge and Transmembrane Domains of Chimeric  Antigen Receptor Regulate Receptor Expression and Signaling Threshold
Cells | Free Full-Text | Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate Receptor Expression and Signaling Threshold

Frontiers | The CD28-Transmembrane Domain Mediates Chimeric Antigen  Receptor Heterodimerization With CD28
Frontiers | The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28

Modeling of hinge-hinge interactions. The extracellular part of the... |  Download Scientific Diagram
Modeling of hinge-hinge interactions. The extracellular part of the... | Download Scientific Diagram

Frontiers | Reducing Hinge Flexibility of CAR-T Cells Prolongs Survival In  Vivo With Low Cytokines Release
Frontiers | Reducing Hinge Flexibility of CAR-T Cells Prolongs Survival In Vivo With Low Cytokines Release